Research Triangle Park, NC, November 20, 2006 - - Jenken Biosciences, Inc., an
emerging specialty pharmaceutical company, today announced that it has signed
a strategic master services agreement valued at up to $2 million with Cato Research
Ltd., a global contract research organization, and Cato BioVentures, its venture
capital affiliate. Under Cato BioVentures' equity-based compensation model, Cato
Research will provide strategic drug development services and regulatory advice
related to the clinical development of JKB-122, Jenken's lead drug candidate for
the treatment or prevention of liver damage associated with hepatitis C and other
diseases associated with organ inflammation.
"Cato BioVentures and Cato Research
are committed to working with early-stage companies like Jenken. When we partner
early, as we have here, we can make a positive difference in the overall development
of promising drug candidates like Jenken's JKB-122, a compound with exciting potential
to impact the treatment of hepatitis C-related inflammatory liver disease," said
Shawn K. Singh, Managing Principal of Cato BioVentures. "This strategic development
agreement is flexible, broad-based and reflects a tight fit between our venture
program and Jenken's innovative drug repurposing model."
"We are very pleased
to begin this relationship with Cato, a leading clinical research organization.
Their drug development resources and regulatory expertise will be extremely valuable
in helping us accomplish multiple 'critical path' objectives for JKB-122," said
Barry Buzogany, Jenken's President and Chief Executive Officer. "The fact that
an organization of Cato's caliber is willing to accept equity-based compensation
from Jenken for a key portion of its services underscores the promise of JKB-122
and our novel approach to discovering and patenting new uses for drugs already
known to be safe. By repurposing drugs, Jenken can substantially reduce the overall
drug development risk, cost and time-to-market."
Importantly, this strategic master
services agreement will also enable Jenken to pursue other investment and loan
resources that will leverage Cato's investment in the company, such as applying
for a matching loan from the North Carolina Biotechnology Center.
In the U.S.,
four million people are infected with the Hepatitis C virus (HCV). Among HCV-infected
patients, 80 percent become chronically infected. Half of these chronically-infected
patients are unresponsive to current antiviral treatments. Jenken's JKB-122 is
focused on restoring liver function in this large non-responder patient group.
JKB-122 is expected to enter Phase 2 clinical development in 2007. Jenken and
Cato expect JKB-122 to have broader application for inflammatory diseases of the
liver, kidneys and lungs.
About Jenken Biosciences
Jenken Biosciences, Inc. is
an early-stage, specialty pharmaceutical company dedicated to "repurposing" (finding
new therapeutic uses for) off-patent, approved drugs. Jenken is currently repurposing
two marketed drugs which could revolutionize the treatment of diseases associated
with chronic organ inflammation. Jenken's drug development strategy is to reduce
time-to-market and to lower risk and development costs by re-profiling approved
drugs and their analogs or metabolites. Jenken was recently selected as one of
only nine early-stage companies from across the East Coast to present at CED's
Opportunity 2006 Conference scheduled for December 4-5, 2006, in Wilmington, North
Carolina. Jenken will also be presenting at The 2006 Venture Summit on November
28, 2006, in Burlington, Massachusetts.
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FOR MORE INFORMATION, CONTACT:
Barry Buzogany
Chief Executive Officer
919-765-0032
bbuzogany@jenkenbio.com
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